当前的 SARS-CoV-2(新冠,COVID-19)冠状病毒疫情大流行带来了许多医疗管理方面的挑战,并存在多重不确定性。其中最受关注的问题之一是针对治疗和预防最合适的药物疗法。目前尚无针对新冠的特效药物治疗方案在高质量研究中证明其有效性和安全性(1)。不过,基于实验性思路已提出多种不同方案,其中之一是使用氯喹(CRQ)及其衍生物,主要是羟氯喹(HCQ)。
The current SARS-CoV-2 (COVID-19) coronavirus pandemic is posing many health management challenges with multiple uncertainties. One of the most relevant is focused on the most suitable pharmacological therapy for cure and prophylaxis. Currently, there is no specific drug treatment for COVID-19 that has demonstrated efficacy and safety in high- quality studies (1). However, different options are being proposed from an experimental approach. One of them is the use of chloroquine (CRQ) and its derivatives, basically hydroxychloroquine (HCQ).